Équipe Biologie et Pathologie du Pancréas Endocrine (B2PE)

Responsable : Jamileh MOVASSAT (PR P7)

Cinq publications récentes

1/Quinault A, Gausseres B, Bailbe D, Chebbah N, Portha B, Movassat J, Tourrel-Cuzin C. Disrupted dynamics of F-actin and insulin granule fusion in INS-1 832/13 beta-cells exposed to glucotoxicity: partial restoration by glucagon-like peptide 1. Biochim Biophys Acta. 2016 Aug;1862(8):1401-11. (Abstract)

2/Liu JJ, Raynal S, Bailbé D, Gausseres B, Carbonne C, Autier V, Movassat J, Kergoat M, Portha B. Expression of the kynurenine pathway enzymes in the pancreatic islet cells. Activation by cytokines and glucolipotoxicity. Biochim Biophys Acta. 2015, May;1852(5):980-91. (Abstract)

3/Chavey A, Bailbé D, Maulny L, Renard JP, Movassat J, Portha B. A euglycaemic/non-diabetic perinatal environment does not alleviate early beta cell mal development and type 2 diabetes risk in the GK/Par rat model. Diabetologia. 2013, Jan;56(1):194-203. (Abstract)

4/Figeac F, Ilias A, Bailbe D, Portha B, Movassat J. Local in vivo GSK3β knockdown promotes pancreatic β cell and acinar cell regeneration in 90% pancreatectomized rat. Mol Ther. 2012 Oct;20(10):1944-52. (Abstract)

5/Auffret J, Freemark M, Carré N, Mathieu Y, Tourrel-Cuzin C, Lombès M, Movassat J, Binart N. Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period. Am J Physiol Endocrinol Metab. 2013 Nov 15;305(10):E1309-18. (Abstract)

Publications indexées dans PubMed (depuis 2012)

Quinault A, Gausseres B, Bailbe D, Chebbah N, Portha B, Movassat J, Tourrel-Cuzin C. Disrupteddynamics of F-actin and insulin granule fusion inINS-1 832/13 beta-cells exposed to glucotoxicity : partial restoration byglucagon-like peptide 1. Biochim Biophys Acta. 2016 1862(8):1401-11.

Macia M, Pecchi E, Vilmen C, Desrois M, Lan C, Portha B, Bernard M, Bendahan D, Giannesini B. Insulin Resistance Is Not Associated with an Impaired Mitochondrial Function in Contracting Gastrocnemius Muscle of Goto-Kakizaki Diabetic Rats In Vivo. PLoS One. 2015 10(6):e0129579.

Delabar JM, Latour A, Noll C, Renon M, Salameh S, Paul JL, Arbones M, Movassat J, Janel N. One-carbon cycle alterations induced by Dyrk1a dosage. Mol Genet Metab Rep. 2014, 1:487-492.

Medjber K, Freidja ML, Grelet S, Lorenzato M, Maouche K, Nawrocki-Raby B, Birembaut P, Polette M, Tournier JM. Role of nicotinic acetylcholine receptors incell proliferation and tumour invasion in broncho-pulmonary carcinomas. Lung Cancer. 2015, 87:258-64.

Khayati F, Pérez-Cano L, Maouche K, Sadoux A, Boutalbi Z, Podgorniak MP,Maskos U, Setterblad N, Janin A, Calvo F, Lebbé C, Menashi S, Fernandez-Recio J, Mourah S. EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF. Oncotarget. 2015, 6(12):9766-80.

Liu JJ, Raynal S, Bailbé D, Gausseres B, Carbonne C, Autier V, Movassat J, Kergoat M, Portha B. Expression of the kynurenine pathway enzymes in the pancreatic islet cells. Activation by cytokines and glucolipotoxicity. Biochim Biophys Acta. 2015, 1852(5):980-91.

Planchais J, Boutant M, Fauveau V, Qing LD, Sabra-Makke L, Bossard P,Vasseur-Cognet M, Pégorier JP. The role of chicken ovalbumin upstream promoter transcription factor II in the regulation of hepatic fatty acid oxidation and gluconeogenesis in newborn mice. Am J Physiol Endocrinol Metab. 2015, 308(10):E868-78.

Delyon J, Khayati F, Djaafri I, Podgorniak MP, Sadoux A, Setterblad N, Boutalbi Z, Maouche K, Maskos U, Menashi S, Lebbé, Mourah S. EMMPRIN regulates ßintegrin-mediated adhesion through Kindlin-3 in human melanoma cells. Exp Dermatol. 2015, 24(6):443-8.

Calderari S, Irminger JC, Giroix MH, Ehses JA, Gangnerau MN, Coulaud J,Rickenbach K, Gauguier D, Halban P, Serradas P, Homo-Delarche F. Regenerating 1and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats. PLoS One. 2014, 9(2):e90045.

Portha B, Fournier A, Kioon MD, Mezger V, Movassat J. Early environmental factors, alteration of epigenetic marks and metabolic disease susceptibility. Biochimie. 2014, 97:1-15.

Somm E, Guérardel A, Maouche K, Toulotte A, Veyrat-Durebex C, Rohner-Jeanrenaud F, Maskos U, Hüppi PS, Schwitzgebel VM. Concomitant alpha7 and beta2 nicotinic AChR subunit deficiency leads to impaired energy homeostasis and increased physical activity in mice. Mol Genet Metab. 2014, 112(1):64-72.

Chavey A, Ah Kioon MD, Bailbé D, Movassat J, Portha B. Maternal diabetes, programming of beta-cell disorders and intergenerational risk of type 2 diabetes. Diabetes Metab. 2014, 40(5):323-30.

Bailbé D, Philippe E, Gorbunov E, Tarasov S, Epstein O, Portha B. The novel oral drug Subetta exerts an antidiabetic effect in the diabetic Goto-Kakizaki rat : comparison with rosiglitazone. J Diabetes Res. 2013, 2013:763125.

Islam MS, Koya D, Portha B. Animal models of diabetes and its associated complications. J Diabetes Res. 2013, 2013:593204.

Chavey A, Bailbé D, Maulny L, Renard JP, Movassat J, Portha B. A euglycaemic/non-diabetic perinatal environment does not alleviate early beta cell maldevelopment and type 2 diabetes risk in the GK/Par rat model. Diabetologia. 2013, 56(1):194-203.

Jurysta C, Nicaise C, Giroix MH, Cetik S, Malaisse WJ, Sener A. Comparison ofGLUT1, GLUT2, GLUT4 and SGLT1 mRNA expression in the salivary glands and six other organs of control, streptozotocin-induced and Goto-Kakizaki diabetic rats. Cell Physiol Biochem. 2013, 31(1):37-43.

Castell-Auví A, Cedó L, Movassat J, Portha B, Sánchez-Cabo F, Pallarès V,Blay M, Pinent M, Ardévol A. Procyanidins modulate microRNA expression in pancreatic islets. J Agric Food Chem. 2013, 61(2):355-63.

Véret J, Coant N, Gorshkova IA, Giussani P, Fradet M, Riccitelli E, SkobelevaA, Goya J, Kassis N, Natarajan V, Portha B, Berdyshev EV, Le Stunff H. Role of palmitate-induced sphingoid base-1-phosphate biosynthesis in INS-1 β-cell survival. Biochim Biophys Acta. 2013, 831(2):251-62.

Maouche K, Medjber K, Zahm JM, Delavoie F, Terryn C, Coraux C, Pons S, Cloëz-Tayarani I, Maskos U, Birembaut P, Tournier JM. Contribution of α7nicotinicreceptor to airway epithelium dysfunction under nicotine exposure. Proc Natl Acad Sci USA. 2013, 110(10):4099-104.

Sabra-Makke L, Maritan M, Planchais J, Boutant M, Pégorier JP, Even PC, Vasseur-Cognet M, Bossard P. Hypothalamic ventromedial COUP-TFII protects against hypoglycemia-associated autonomic failure. Proc Natl Acad Sci USA. 2013, 110(11):4333-8.

Auffret J, Freemark M, Carré N, Mathieu Y, Tourrel-Cuzin C, Lombès M, Movassat J, Binart N. Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period. Am J Physiol Endocrinol Metab. 2013, 305(10):E1309-18

Figeac F, Ilias A, Bailbe D, Portha B, Movassat J. Local in vivo GSK3β knockdown promotes pancreatic β cell and acinar cell regeneration in 90% pancreatectomized rat. Mol Ther. 2012 10:1944-1952.

Lucas S, Taront S, Magnan C, Fauconnier L, Delacre M, Macia L, Delanoye A, Verwaerde C, Spriet C, Saule P, Goormachtigh G, Héliot L, Ktorza A, Movassat J, Polakowska R, Auriault C, Poulain-Godefroy O, Di Santo J, Froguel P, Wolowczuk I. Interleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanisms. PLoS One. 2012 7(6):e40351.

Boutant M, Ramos OH, Tourrel-Cuzin C, Movassat J, Ilias A,Vallois D, Planchais J, Pégorier JP, Schuit F, Petit PX, Bossard P, Maedler K, Grapin-Botton A, Vasseur-Cognet M. 04. Carneiro L, Allard C, Guissard C, Fioramonti X, Tourrel-Cuzin C, Bailbe D, Barreau C, Offer G, Nedelec E, Salin B, Rigoulet M, Belenguer P, Pénicaud L, Leloup C. Importance of mitochondrial Dynamin Related Protein 1 (DRP1) in hypothalamic glucose sensitivity in rats. Antioxid Redox Signal. 2012 17(3):433-44.

Papazoglou I, Berthou, Vicaire N, Rouch C, Markaki EM, Bailbe D, Portha B, Taouis, M, Gerozissis K. Hypothalamic serotonin-insulin signaling cross-talk and alterations in a type 2 diabetic model. Mol Cell Endocrinol. 2012 350:136–144(2012).

Portha B, Giroix MH, Tourrel-Cuzin C, Le Stunff H, Movassat J. The GK rat : a prototype for the study of non-overweight type 2 diabetes. Methods Mol Biol. 2012 933:125-59.